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John Lyftogt, MD ( http://www.lyftogtmed.com ) is a physician from New Zealand that has been using dextrose to treat many types of pain since 2002. He has been developing a new paradigm on the causes of pain since his first observations that dextrose can have an immediate effect on many different types of pain. He is the pioneer behind the technique known as Lyftogt Perineural Injection Therapy. The science of the effect of dextrose on the nerves is very complex and not yet fully understood, but the collaboration of Dr. Lyftogt with physicians and scientists from all over the world is putting the pieces of the puzzle together.
Perineural Injection Therapy (PIT) is a procedure where small amounts of buffered dextrose solution is injected around nerves. Specific sites are targeted where the nerves penetrate through fascia, muscle and bone (Chronic Constriction Injury) or where the nerves become irritated as they rub over boney surfaces (Friction Syndrome). When nerves become irritated or injured, they swell causing increased numbers of a pain receptors (TRPV1) on the surface. This swelling also leads to less oxygen (hypoxia) and energy (dextrose) getting to the nerve. These dysfunctional nerves emit chemicals (Substance P, CGRP) which is called Neurogenic Inflammation. Substance P is known to cause swelling, pain, muscle tightness and stimulation of immune-mediated inflammation. It has even been shown to contribute to depression and anxiety due to its effects on the brain. CGRP causes tendon degeneration and calcification, thinning of bones and swelling of tissue as well.
Whole Body pain or Fibromyalgia is most likely due to chronic dysfunction of the small nerves diffusely throughout the body. One of the substances associated with Neurogenic Inflammation is called Substance P (the P stands for PAIN!). Substance P has been shown to contribute to anxiety and depression due to its effects on parts of the brain. We have developed a protocol that helps decrease the pain associated with Fibromyalgia (and its effects on the brain).
Other common forms of nerve pain and dysfunction that can be improved with PIT are post-herpetic neuralgia, diabetic neuropathy, facial weakness that persists after Bell’s Palsy, Restless Leg Syndrome, CRPS (Chronic Regional Pain Syndrome) and other forms of neuropathic pain.
If your pain interferes with your ability to “walk, work, sleep or enjoy life”, call MD 2.0 to set up a consultation
Additional Reading on the Science of PIT and Nerve Pain:
Perineural Injection Therapy in the treatment of CRPS
Nociceptors and the Perception of Pain
Activation of C fibers by metabolic perturbations associated with tourniquet ischemia
“One of the most gratifying aspects of my clinic is seeing a patient walk in with debilitating pain and walk out feeling dramatically improved. Treating acute or chronic pain has been one of the motivating factors for my pursuit in learning Neural Prolotherapy. It is amazing to myself and the patient to have their pain extinguished. I have received more than one hug for treating patients that suffer from this severe pain.”
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